Hi!
Yep, you can use them, depends on which browsers you need to support and if the polyfills won’t impact the final results in older browsers.
Here you can find an article on the topic: https://medium.com/javascript-in-plain-english/create-micro-frontends-using-web-components-with-support-for-angular-and-react-2d6db18f557a

I hope this helps